Hepatocellular Carcinoma Conclusions:
CyberKnife® radiosurgery effectively addresses the technical limitations of other radiotherapy methods, producing precise ablative radiation coverage of the HCC lesion, and accurately tracking the lesion as it moves with respiration, in a manner whose precision is unequaled by other radiation delivery systems. It may be reasonably be applied as an aggressive “bridge therapy” in a HCC patient awaiting removal of their diseased liver and liver transplantation, either alone or in combination with other therapies, or it may be used as a radiosurgical ablative method with curative intent in selected patients for whom traditional surgery is not an option. Further study of this treatment method in HCC patients is warranted.