Recurrent Disease
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Site specific stereotactic radiosurgery/radiotherapy retreatment literature:
Head and neck/Skull base lesions
There is considerable evidence that radiosurgical salvage of post-radiotherapy skull base and nasopharynx relapses provides durable local control in a high percentage of patients, with an apparently lower complication rate than seen with conventional reirradiation techniques (31, 32, 33, 34, 35, 36). The preponderance of published radiosurgery experience for recurrent head and neck lesions has been gained with Gamma Knife single fraction radiosurgery.
Head and neck/Skull base lesions
There is considerable evidence that radiosurgical salvage of post-radiotherapy skull base and nasopharynx relapses provides durable local control in a high percentage of patients, with an apparently lower complication rate than seen with conventional reirradiation techniques (31, 32, 33, 34, 35, 36). The preponderance of published radiosurgery experience for recurrent head and neck lesions has been gained with Gamma Knife single fraction radiosurgery.
The frameless CyberKnife® design, multiple fractionation capability, and virtually unlimited dose-coverage capability compared with Gamma Knife indicates a much larger spectrum of applicability to recurrent head and neck lesions with CyberKnife®.
Case Studies:
Left Optic Nerve Meningioma (WHO Grade 2)
Barrow Neurological Institute
Meningioma (Optic Chiasm)
Stanford University Medical Center
See Also:
Recurrent Head & Neck Cancers
Images adapted from
"Robotic Radiosurgery" - First Edition
Written by Donald B. Fuller, M.D. – Radiation Oncologist