Radiotherapy for Melanoma:
Brain metastases
In contradistinction to the relatively favorable response rate of soft tissue melanoma metastases reported in the RTOG study (16), melanoma metastatic to the brain responds poorly to conventional radiotherapy, with a reported 3 month median survival – a response that barely exceeded supportive care only (9). More favorable survival in this setting has been reported with surgical resection with or without post-operative whole brain radiotherapy (9).