CyberKnife® Radiosurgery:
Targeting Angles
Traditional radiotherapy systems target the lesion from a relatively small number of fixed positions. In contrast, the inherently noncoplanar geometry of the CyberKnife® device allows literally hundreds of targeting angles to be selected, increasing the ability to conform the ablative dose to the target lesion within the kidney, while better sparing the adjacent renal parynchema and surrounding normal GI tissues.

The accuracy of this model has been validated in a study of porcine kidneys, in live animals treated with CyberKnife® radiosurgery, with histologic sections of focally targeted renal tissue, revealing total histological destruction devoid of all cellular elements within the targeted zone by 8 weeks post-treatment, with preserved renal tissue adjacent to the zone of sharply marginated histological annihilation (28).